Tennessee and Florida will face off in a pivotal SEC East meeting at 3:30 p.m. ET on Saturday, Sept. 16. The Gators are a 4-point favorite. Find full odds and our picks on the game below.

The is the 24th time the two teams have both been ranked when meeting. Florida is 15-8 in those Top 25 showdowns.

The Vols (2-0) beat Indiana State last week and edged Georgia Tech 42-41 in double overtime in Week 1. The Gators (0-1) lost their opener against Michigan 33-17 in Arlington, Texas, and had their second game canceled because of Hurricane Irma.

Tennessee-Florida, Week 3 betting odds

Florida is a 4-point favorite, according to MyBookie. The over/under is 48.5 points.

Tennessee-Florida betting picks

Mike Griffith’s pick: Florida 24, Tennessee 17

“Teams appear evenly matched in terms of talent and working in new quarterbacks, so Gators are the pick based on intangibles such as home field and having fresher legs.”

Blake Morgan’s pick: Tennessee 21, Florida 10

“Tennessee has struggled to find consistency on the offensive end this season, but it will find its footing quicker than Florida in a sloppy game in Gainesville.”

Dustin Dopirak’s pick: Tennessee 17, Florida 10

“Every year since 2014 when I started covering the beat, I thought Tennessee had the more talented team in this matchup. I think so again this year. But I’ve been proven wrong before.”

Josh Ward’s pick: Florida 17, Tennessee 16

“This game will likely come down to which team protects the football and makes the fewest mistakes. The Gators have the edge in that battle, thanks to the home crowd.”

Tennessee-Florida betting preview

  • Florida leads the all-time series 26-20. The Gators owned an 11-game winning streak until the Vols won last season 38-28 in Knoxville, Tenn.
  • The Gators own a 13-5 advantage in Gainesville, where the game will be played Saturday, Sept. 16.
  • The last time Tennessee won at The Swamp was 2003, when Jabari Davis ran for two touchdowns in a 24-10 victory.
  • Tennessee coach Butch Jones is 32-21 with the Vols and 14-18 in the SEC. They are 18-8 overall the past two seasons and 9-7 in league games.
  • If you’re looking for trends Saturday, teams coached by Jones are 67-6 when leading at halftime and 57-10 when leading after the first quarter

    What you need to know about Tennessee-Florida

    • Tennessee learned Friday it will be without senior safety Todd Kelly Jr.. Last year’s tackles leader is out indefinitely with knee injury.
    • Tennessee will also be without WR Jauan Jennings (wrist), preseason All-SEC MLB Darrin Kirkland Jr. (knee) and RT Chance Hall (knee). All three projected starting upperclassmen have been among the preseason injuries the Vols have suffered.
    • Kick return man Evan Berry (hamstring) is questionable for the game.
    • The Vols will be without tight end Eli Wolf, cornerback Baylen Buchanan and linebacker Austin Smith.
    • Saturday’s game marks the second straight season but only the third time since 2007 that both teams have been ranked in the Top 25 at the time of their meeting.
    • Florida holds a 26-20 advantage in the all-time series, including a 13-5 edge in games played against Tennessee in Gainesville.
    • The Gators have won their last 27 home-opening games and have not started a season 0-2 since 1971.
    • Tennessee scored 38 points against Florida in the most recent game between the teams, erasing a 21-3 halftime deficit for a 38-28 victory over the Gators.
    • Vols tailback John Kelly is the only player in the SEC who leads his team in rushing (208 yards) and receptions (10) this season.
    • Tennessee has 27 players on the traveling squad of 70 who will make their first appearance at Florida.
    • Only 13 percent of the yardage Tennessee accumulated in last year’s game was generated by players still on the roster.
    • Ty Chandler’s 91-yard kick return for Tennessee last Saturday was the 11th special teams touchdown of the Butch Jones coaching era in Knoxville (since 2013). The Vols have 5 TDs off kick returns in that span, a mark bettered only by San Diego State (7).
    • Tennessee sophomore linebacker Daniel Bituli has had a breakout start to the season. Bituli’s 23 tackles in the season-opening 42-41 double-overtime win against Georgia Tech were the most by a Vols player since 1988.
    • Florida has a 20-6 record against Tennessee since 1991.

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